DelveInsight’s, “Merkel Cell Carcinoma Pipeline Insight, 2023,” report provides comprehensive insights about 14+ companies and 14+ pipeline drugs in the Merkel Cell Carcinoma pipeline landscape. It covers the Merkel Cell Carcinoma pipeline drug profiles, including Merkel Cell Carcinoma clinical trials and nonclinical stage products. It also covers the Merkel Cell Carcinoma pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
For Merkel Cell Carcinoma Emerging drugs, the Merkel Cell Carcinoma pipeline analysis report provides a 360° view of the therapeutics landscape by development point, product type, route of administration, molecule type, and MOA. The Merkel Cell Carcinoma pipeline research covers business opportunities, challenges, future partnerships, strong competitors, and growth strategies.
In the Merkel Cell Carcinoma Pipeline Report, a detailed description of the drug is given which includes the mechanism of action of the drug, Merkel Cell Carcinoma clinical trials studies, Merkel Cell Carcinoma NDA approvals (if any), and product development activities comprising the technology, Merkel Cell Carcinoma collaborations, licensing, mergers and acquisition, funding, designations, and other product-related details.
Key takeaways from the Merkel Cell Carcinoma Pipeline Report
DelveInsight’s Merkel Cell Carcinoma Pipeline analysis depicts a robust space with 14+ active players working to develop 14+ pipeline treatment therapies.
The leading Merkel Cell Carcinoma Companies includes ImmunityBio, OncoSec Medical, Exelixis, 4SC, Kartos therapeutics, Incyte corporation, Amgen, BioInvent International AB, SOTIO Biotech, Xencor, Exicure, Checkmate Pharmaceuticals, Takeda, Genocea Biosciences, NeoImmuneTech, Sensei Biotherapeutics, and others.
Promising Merkel Cell Carcinoma Pipeline Therapies includes XmAb18087, XmAb18087 ± Pembrolizumab, GLA-SE, Pembrolizumab (MK-3475), Retifanlimab, Pasireotide sub-cutaneous formulation Tavokinogene Telseplasmid (tavo), Avelumab, MLN0128, Nivolumab, and others.
The Merkel Cell Carcinoma companies and academics are working to assess challenges and seek opportunities that could influence Merkel Cell Carcinoma R&D. The Merkel Cell Carcinoma pipeline therapies under development are focused on novel approaches to treat/improve Merkel Cell Carcinoma.
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Merkel Cell Carcinoma Overview
Merkel cell carcinoma (MCC) is a rare, aggressive form of skin cancer with a high risk for returning (recurring) and spreading (metastasizing), often within two to three years after initial diagnosis. Merkel cells are located deep in the top layer of skin. Merkel cells are connected to nerves, signaling touch sensation as “touch receptors.” MCC tumors often, but not always, appear on sun-exposed areas of the body. The tumors are not nearly as distinctive as other skin cancers and can appear as a pearly pimple-like lump, sometimes skin-colored, red, purple or bluish-red, though they are rarely tender to the touch. Treatments for Merkel cell carcinoma can include: surgery, Radiation therapy, immunotherapy, and chemotherapy.
Recent Developmental Activities in the Merkel Cell Carcinoma Treatment Landscape
The U.S. Food and Drug Administration (FDA) has granted two Fast Track designations to cavrotolimod (AST-008). Exicure initiated the Phase II stage of the clinical trial with dose-expansion cohorts of intratumoral cavrotolimod in combination with approved checkpoint inhibitors to treat two cohorts of patients with locally advanced or metastatic MCC or CSCC.
4SC has also signed a drug supply agreement with Merck KGaA for avelumab (anti-PD-L1 antibody) to conduct a Phase II clinical trial of domatinostat in combination with avelumab in advanced-stage Merkel cell carcinoma (MCC) patients progressing on previous anti-PD-(L)1 monotherapy (MERKLIN 2).
For further information, refer to the detailed Merkel Cell Carcinoma Drugs Launch, Merkel Cell Carcinoma Developmental Activities, and Merkel Cell Carcinoma News, click here for Merkel Cell Carcinoma Ongoing Clinical Trial Analysis
Merkel Cell Carcinoma Pipeline Therapeutics Assessment
There are approx. 14+ key companies which are developing the therapies for Merkel Cell Carcinoma. The companies which have their Merkel Cell Carcinoma drug candidates in the most advanced stage, i.e. Phase II include, 4SC.
Merkel Cell Carcinoma Pipeline Segmentation
Phases
Late stage products (Phase III)
Mid-stage products (Phase II)
Early-stage product (Phase I) along with the details of
Pre-clinical and Discovery stage candidates
Discontinued & Inactive candidates
Route of Administration
Route of Administration
Oral
Parenteral
Intravenous
Subcutaneous
Topical
Molecule Type
Monoclonal Antibody
Peptides
Polymer
Small molecule
Gene therapy
Product Type
Find out more about the Merkel Cell Carcinoma Pipeline Segmentation, Therapeutics Assessment, and Merkel Cell Carcinoma Emerging Drugs @ Merkel Cell Carcinoma Treatment Landscape
Scope of the Merkel Cell Carcinoma Pipeline Report
Coverage- Global
Merkel Cell Carcinoma Companies- ImmunityBio, OncoSec Medical, Exelixis, 4SC, Kartos therapeutics, Incyte corporation, Amgen, BioInvent International AB, SOTIO Biotech, Xencor, Exicure, Checkmate Pharmaceuticals, Takeda, Genocea Biosciences, NeoImmuneTech, Sensei Biotherapeutics, and others.
Merkel Cell Carcinoma Pipeline Therapies includes XmAb18087, XmAb18087 ± Pembrolizumab, GLA-SE, Pembrolizumab (MK-3475), Retifanlimab, Pasireotide sub-cutaneous formulation Tavokinogene Telseplasmid (tavo), Avelumab, MLN0128, Nivolumab, and others.
Merkel Cell Carcinoma Pipeline Segmentation: Product Type, Molecule Type, Route of Administration, Mechanism of Action
Dive deep into rich insights for drugs for Merkel Cell Carcinoma Pipeline Companies and Therapies, click here @ Merkel Cell Carcinoma Unmet Needs and Analyst Views
Table of Content
Introduction
Executive Summary
Merkel Cell Carcinoma: Overview
Pipeline Therapeutics
Therapeutic Assessment
Mid Stage Products (Phase II)
Domatinostat: 4SC
Drug profiles in the detailed report…..
Early Stage Products (Phase I/II)
XmAb18087: Xencor
Drug profiles in the detailed report…..
Preclinical stage products
SNS-401-NG: Sensei Biotherapeutics
Drug profiles in the detailed report…..
Inactive Products
Merkel Cell Carcinoma Key Companies
Merkel Cell Carcinoma Key Products
Merkel Cell Carcinoma- Unmet Needs
Merkel Cell Carcinoma- Market Drivers and Barriers
Merkel Cell Carcinoma- Future Perspectives and Conclusion
Merkel Cell Carcinoma Analyst Views
Merkel Cell Carcinoma Key Companies
Appendix
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