Open-Angle Glaucoma Market Insights, Market Drivers, Market Barriers, Emerging Therapy and Market Report Scope

DelveInsight’s Open-angle glaucoma Market Insights report provides a thorough understanding of current treatment practices, emerging drugs, Open-angle glaucoma market share of the individual therapies, current and forecasted Open-angle glaucoma market size from 2019 to 2032 segmented into 7MM (the USA, EU5 (the UK, Italy, Spain, France, and Germany), and Japan).


Open-Angle Glaucoma Overview

Glaucoma describes a group of conditions in which there is characteristic cupping of the optic disc with corresponding visual field defects, due to retinal ganglion cell loss. It is a progressive condition and the most common cause of irreversible blindness worldwide.


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Some of the key features of the Open-Angle Glaucoma Market Report

As per DelveInsight’s analysis, a higher percentage of diagnosed prevalence was observed for females, in comparison to males, in all the 7MM countries.
According to DelveInsight’s analysis, in 2019, there were 2,749,378 cases of Open-Angle Glaucoma in the US.
DelveInsight’s analysis shows that in 2019 there were 7,941,564 and 882,396 cases of POAG and Secondary OAG, respectively, in the 7MM.
Open-Angle Glaucoma companies such as Aerie Pharmaceuticals, Sun Pharma Advanced Research Company Limited, Santen Pharmaceutical, Bausch and Lomb, D.Western Therapeutics Institute (DWTI)/Kowa LTD., Alcon Research, Merck Sharp & Dohme Corp, Novartis/Alcon Research, Allergan, and several others.
Open Angle Glaucoma therapies such as ROCKLATAN, Rhopressa, XELPROS (latanoprost ophthalmic emulsion) 0.005%, EYBELIS Ophthalmic Solution 0.002% (DE-117, Omidenepag isopropyl), VYZULTA, TAPCOM/ DE-111 (Tafluprost/timolol maleate), GLANATEC, Simbrinza (brinzolamide/brimonidine tartrate ophthalmic suspension) 1%/0.2%, ZIOPTAN (tafluprost), DuoTrav PQ (travoprost/timolol), TRAVATAN Z (travoprost ophthalmic solution) 0.004%, LUMIGAN 0.01% (bimatoprost ophthalmic solution), Bimatoprost SR (Sustained-Release), and several others.


Open-Angle Glaucoma Categories

The two major categories of glaucoma are

Open-angle glaucoma,
And Narrow-angle glaucoma.


Open-Angle Glaucoma Types

Primary open-angle glaucoma (POAG) and Secondary open-angle glaucoma. POAG is a subset of glaucoma defined by an open, normal-appearing anterior chamber angle and raised intraocular pressure (IOP), with no other underlying disease. In Secondary open-angle glaucoma, there is an identifiable cause of increased eye pressure, resulting in optic nerve damage and vision loss.


Open-Angle Glaucoma Symptoms

The sign and symptoms of OAG includes an increase in IOP, open anterior chamber angle and optic disc changes seen on clinical examination such as high cup to disc ratio, cup to disc ratio asymmetry between eyes, vertical elongation of the cup, etc.


Open-Angle Glaucoma Risk Factors

The risk factors of OAG include older age, family history of glaucoma, African ancestry, nearsightedness, high IOP, low blood pressure, use of topical corticosteroids, inflammation, and tumor. There are several risk factors like age >60 years, genetic predisposition, certain eye characteristics (such as a pupillary defect, thin cornea, myopia), low educational status, smoking, African descent, and visual problems, which are associated with this indication and, thus, the treatment pattern varies accordingly.


Open-Angle Glaucoma Classification

POAG is classified based on the age of onset, as primary congenital glaucoma (onset up to 3 years of age), juvenile open-angle glaucoma (JOAG; onset at 5–35 years), and adult-onset POAG (after the age of 35 years).


Open-Angle Glaucoma Epidemiology Segmentation in the 7MM

Total Prevalent Population
Gender-specific Diagnosed Prevalence
Age-specific Diagnosed Prevalence
Total Diagnosed Prevalent Population
Type-specific Diagnosed Prevalent Population


Open-Angle Glaucoma Treatment

The main goal of glaucoma treatment is to increase the quality of life through the reduction of IOP to preserve visual function. In the process of IOP reduction, an ideal medication should have a schedule that is simple to follow, be least interrupting with a patient’s life, highly tolerable, and affordable. However, the medical treatment of glaucoma has associated side effects, complications, and costs.


Open-Angle Glaucoma Market Insights

There are three mainstays for lowering eye pressure, i.e. medication, laser, and surgery. The two types of laser treatments currently used are Selective Laser Trabeculoplasty (SLT) and Argon Laser Trabeculoplasty (ALT). Surgery for OAG includes Cataract Surgery, Micro-Invasive Glaucoma Surgery (MIGS), Trabeculectomy, Drainage Implant Surgery, and Ciliary Body Ablation. There is an array of medications to lower the intraocular pressure in OAG, which are divided into five major classes, i.e., Prostaglandin Analogs, Beta Blockers, Diuretics, Cholinergic Agonists (Parasympthomimetics), and Alpha Agonists.


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Open-Angle Glaucoma Emerging Therapy Assessment

Open-Angle Glaucoma Treatment aims to lower the IOP and thus reduce the risk of progressive loss of vision, using medications, laser therapy, or conventional surgery. Open-Angle Glaucoma Treatment options are rapidly expanding. However, there is no cure available still.


Open-Angle Glaucoma Market Drivers

Rich emerging pipeline
Development of advanced anti-glaucoma medications
Patient-friendly dosage regimes
Rise in awareness
Development of treatment methods to tackle the situation of non-adherence


Open-Angle Glaucoma Market Barriers

Lack of animal models
Socioeconomic barriers
Lack of patient pool due to under-diagnosis


Table of Content

1. Key Insights

2. Executive Summary of Open-Angle Glaucoma

3. Competitive Intelligence Analysis for Open-Angle Glaucoma

4. Open-Angle Glaucoma: Market Overview at a Glance

5. Open-Angle Glaucoma: Disease Background and Overview

6. Patient Journey

7. Open-Angle Glaucoma Epidemiology and Patient Population

8. Treatment Algorithm, Current Treatment, and Medical Practices

9. Open-Angle Glaucoma Unmet Needs

10. Key Endpoints of Open-Angle Glaucoma Treatment

11. Open-Angle Glaucoma Marketed Products

12. Open-Angle Glaucoma Emerging Therapies

13. Open-Angle Glaucoma: Seven Major Market Analysis

14. Attribute analysis

15. 7MM: Market Outlook

16. Access and Reimbursement Overview of Open-Angle Glaucoma

17. KOL Views

18. Market Drivers

19. Market Barriers

20. Appendix

21. DelveInsight Capabilities

22. Disclaimer

23. About DelveInsight


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