Metastatic Merkel Cell Carcinoma Market to Observe Stupendous Growth During the Forecast Period – DelveInsight | Key Companies – Merck, Morphogenesis, NantKwest, Kartos Therapeutics, and Incyte

Delveinsight Business Research LLP
DelveInsight’s “Metastatic Merkel Cell Carcinoma Market Insights, Epidemiology, and Market Forecast 2032” report delivers an in-depth understanding of the disease, historical and forecasted epidemiology as well as the Metastatic Merkel Cell Carcinoma Market Size and Share in the 7MM (i.e. the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan).

The Metastatic Merkel Cell Carcinoma market report covers emerging drugs, current treatment practices, market share of the individual therapies, current and forecasted market size from 2019 to 2032. It also evaluates the current treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market. 

Metastatic Merkel Cell Carcinoma: An Overview

Merkel Cell Carcinoma (MCC) is a rare, highly aggressive neuroendocrine cutaneous neoplasm with a variable clinical presentation. It is a predominantly dermal-based lesion composed of monotonous small round cells with scanty cytoplasm, often difficult to differentiate from small round cell tumors, metastatic small cell carcinoma, blastic hematologic malignancies, and melanoma.

In most people, the first sign of Merkel cell carcinoma is a small bump (nodule) on the skin. This bump is usually firm and appears either skin-colored or red-purple. It also tends to grow rapidly. Often, there no symptoms associated with the nodule.

Merkel cell carcinoma tends to grow quickly and metastasize (spread) at an early stage. It usually spreads first to nearby lymph nodes and then may spread to lymph nodes or skin in distant parts of the body, lungs, brain, bones, or other organs.

Treatment of stage IV Merkel cell carcinoma may include the following: Immunotherapy (immune checkpoint inhibitor therapy using avelumab or pembrolizumab). Chemotherapy, surgery, or radiation therapy as palliative treatment to relieve symptoms and improve quality of life.

Metastatic Merkel Cell Carcinoma Market Key Facts

As per DirkSchadendorf et al. (2016), In a study of over 14,000 patients, 50.6% of patients presented with local disease, 35.4% with nodal disease, and 13.5% with distant metastatic MCC.

As per the study conducted by Kelly G. Paulson et al. (2017), Merkel cell carcinoma (MCC) is a neuroendocrine skin cancer with high metastatic potential, with one-third to one-half of patients developing recurrence or metastasis.

As per the National Organization for Rare Disorders 2019: Approximately 60% of MCC tumors arise in men. In the past 15 years, the incidence has tripled in the United States, and it can be lethal for about one-third of the people affected.

As of 2015, approximately 2500 persons per year are diagnosed with this cancer in the United States.

Metastatic Merkel Cell Carcinoma Market

Metastatic Merkel Cell Carcinoma Market Size is anticipated to increase during the study period owing to the rise in the number of Incident population of Metastatic Merkel Cell Carcinoma patients in the 7MM. Extensive R&D activities by academia and industries and the expected launch of therapies will also fuel the market growth.

The market outlook section of the report helps to build a detailed comprehension of the historic, current, and forecasted Metastatic Merkel Cell Carcinoma market size by analyzing the impact of current and emerging therapies in the market. It also provides a detailed assessment of the market drivers & barriers, unmet needs, and emerging technologies.

The report gives a thorough detail of the Metastatic Merkel Cell Carcinoma market trend for each marketed drug and late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action (MoA), competition with other therapies, brand value, their impact on the market and view of the key opinion leaders.

Metastatic Merkel Cell Carcinoma Epidemiology

The epidemiology section covers insights about the historical and current Metastatic Merkel Cell Carcinoma patient pool and forecasted trends for every seven major countries (7MM)  from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides the diagnosed patient pool and their trends along with assumptions undertaken.  

Metastatic Merkel Cell Carcinoma Epidemiology Segmentation

Total Incident Population of Merkel Cell Carcinoma

Gender-specific Cases of Metastatic Merkel Cell Carcinoma

Incident Population of Metastatic Merkel Cell Carcinoma

Diagnosed and Treatable cases of Metastatic Merkel Cell Carcinoma

Metastatic Merkel Cell Carcinoma Drugs Uptake and Pipeline Development Activities

The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Metastatic Merkel Cell Carcinoma market or expected to get launched in the market during the study period. The analysis covers Metastatic Merkel Cell Carcinoma market uptake by drugs; patient uptake by therapies; and sales of each drug. 

Report’s Drugs Uptake section helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

The report also covers the Metastatic Merkel Cell Carcinoma Pipeline Development Activities and provides valuable insights about different therapeutic candidates in Phase II, and Phase III stages and the key companies in the market involved in developing targeted therapeutics. It also analyses the recent Development such as collaborations, acquisitions, and mergers, licensing patent details, and other information for emerging therapies.

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Metastatic Merkel Cell Carcinoma Therapeutics Analysis

Globally, various companies  are involved in developing effective therapies for Metastatic Merkel Cell Carcinoma and further progress in the research and development is likely to translate into a real improvement in the treatment options for Metastatic Merkel Cell Carcinoma

Metastatic Merkel Cell Carcinoma Companies:

Merck

Morphogenesis

NantKwest

Kartos Therapeutics

Incyte Corporation

And others

Metastatic Merkel Cell Carcinoma Therapies covered in the report include:

IFx-Hu2.0

Nivolumab + Ipilimumab

INCMGA00012

haNk and aNK cell therapies

And many more.

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Table of Content

1. Key Insights

2. Executive Summary 

3. Metastatic Merkel Cell Carcinoma Competitive Intelligence Analysis

4. Metastatic Merkel Cell Carcinoma Market Overview at a Glance

5. Metastatic Merkel Cell Carcinoma Disease Background and Overview

6. Metastatic Merkel Cell Carcinoma Patient Journey

7. Metastatic Merkel Cell Carcinoma Epidemiology and Patient Population

8. Metastatic Merkel Cell Carcinoma Treatment Algorithm, Current Treatment, and Medical Practices

9. Metastatic Merkel Cell Carcinoma Unmet Needs

10. Key Endpoints of Metastatic Merkel Cell Carcinoma Treatment

11. Metastatic Merkel Cell Carcinoma Marketed Products

12. Metastatic Merkel Cell Carcinoma Emerging Therapies

13. Metastatic Merkel Cell Carcinoma Seven Major Market Analysis

14. Attribute Analysis

15. Metastatic Merkel Cell Carcinoma Market Outlook (7 major markets)

16. Metastatic Merkel Cell Carcinoma Access and Reimbursement Overview

17. KOL Views on the Metastatic Merkel Cell Carcinoma Market.

18. Metastatic Merkel Cell Carcinoma Market Drivers

19. Metastatic Merkel Cell Carcinoma Market Barriers

20. Appendix

21. DelveInsight Capabilities

22. Disclaimer

*The table of contents is not exhaustive; the final content may vary. 

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