The Alpha-Antitrypsin Deficiency market report covers emerging drugs, current treatment practices, market share of the individual therapies, current and forecasted market size from 2019 to 2032. It also evaluates the current treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market.
Alpha-Antitrypsin Deficiency: An Overview
Alpha Antitrypsin Deficiency is the most common hereditary disorder in which the body is unable to produce a sufficient amount of Alpha-Antitrypsin (AAT) protein. Alpha-Antitrypsin (AAT) protein plays an important role in protecting organs of the body such as the liver and lungs from the harmful effects of proteolytic enzymes such as neutrophil elastase. Thus, AATD leads to an increased risk of developing a liver disease like Cirrhosis, as well as lung diseases such as Emphysema Chronic Obstructive Pulmonary Disease (COPD), and Panniculitis.
Alpha-Antitrypsin Deficiency Market Key Facts
As per DelveInsight estimates, the total Alpha- Antitrypsin Deficiency (AATD) prevalent population in 6 major markets (i.e the United States and EU5 (the United Kingdom, Germany, Italy, France, and Spain) was found to be 1,835,600+ in 2017
Among the EU5 countries, Germany has the highest prevalent population of AATD with 34,300+ cases, followed by the United Kingdom.
Men and women are equally affected by Alpha Antitrypsin Deficiency.
DelveInsight Analysts have observed the population with the PISS allele to have the highest numbers, followed by PISZ. However, the most prevalent type of deficient allele associated with AAT Deficiency is the Z allele.
The Alpha- Antitrypsin Deficiency (AATD) market size is expected to increase during the study period owing to the launch of upcoming therapies.
The market outlook section of the report helps to build a detailed comprehension of the historic, current, and forecasted Alpha-Antitrypsin Deficiency market size by analyzing the impact of current and emerging therapies in the market. It also provides a detailed assessment of the market drivers & barriers, unmet needs, and emerging technologies.
The report gives a thorough detail of the Alpha-Antitrypsin Deficiency market trend for each marketed drug and late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action (MoA), competition with other therapies, brand value, their impact on the market and view of the key opinion leaders.
Alpha-Antitrypsin Deficiency Epidemiology
The epidemiology section covers insights about the historical and current Alpha-Antitrypsin Deficiency patient pool and forecasted trends for every seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides the diagnosed patient pool and their trends along with assumptions undertaken.
Alpha- Antitrypsin Deficiency (AATD) Epidemiology Subtype Segmentation –
Prevalent Population of Alpha Antitrypsin Deficiency
Diagnosed Prevalent Population of Alpha Antitrypsin Deficiency
Gender-Specific Prevalent Population of Alpha Antitrypsin Deficiency
Population at risk of Alpha Antitrypsin Deficiency
Comorbidities associated with Alpha Antitrypsin Deficiency
Alpha-Antitrypsin Deficiency Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Alpha-Antitrypsin Deficiency market or expected to get launched in the market during the study period. The analysis covers Alpha-Antitrypsin Deficiency market uptake by drugs; patient uptake by therapies; and sales of each drug.
Report’s Drugs Uptake section helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
The report also covers the Alpha-Antitrypsin Deficiency Pipeline Development Activities and provides valuable insights about different therapeutic candidates in Phase II, and Phase III stages and the key companies in the market involved in developing targeted therapeutics. It also analyses the recent Development such as collaborations, acquisitions, and mergers, licensing patent details, and other information for emerging therapies.
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Alpha-Antitrypsin Deficiency Therapeutics Analysis
Some of the key companies in the Alpha- Antitrypsin Deficiency (AATD) Market include-
Arrow Head Pharmaceuticals and many others.
Alpha- Antitrypsin Deficiency (AATD) Therapies covered in the report include:
VX-814 & VX-864
Inhaled AAT (also known as Inhaled Alpha-1 Antitrypsin)
And many more.
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Table of Content
1. Key Insights
2. Executive Summary
3. Alpha-Antitrypsin Deficiency Competitive Intelligence Analysis
4. Alpha-Antitrypsin Deficiency Market Overview at a Glance
5. Alpha-Antitrypsin Deficiency Disease Background and Overview
6. Alpha-Antitrypsin Deficiency Patient Journey
7. Alpha-Antitrypsin Deficiency Epidemiology and Patient Population
8. Alpha-Antitrypsin Deficiency Treatment Algorithm, Current Treatment, and Medical Practices
9. Alpha-Antitrypsin Deficiency Unmet Needs
10. Key Endpoints of Alpha-Antitrypsin Deficiency Treatment
11. Alpha-Antitrypsin Deficiency Marketed Products
12. Alpha-Antitrypsin Deficiency Emerging Therapies
13. Alpha-Antitrypsin Deficiency Seven Major Market Analysis
14. Attribute Analysis
15. Alpha-Antitrypsin Deficiency Market Outlook (7 major markets)
16. Alpha-Antitrypsin Deficiency Access and Reimbursement Overview
17. KOL Views on the Alpha-Antitrypsin Deficiency Market.
18. Alpha-Antitrypsin Deficiency Market Drivers
19. Alpha-Antitrypsin Deficiency Market Barriers
21. DelveInsight Capabilities
*The table of contents is not exhaustive; the final content may vary.
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